Amoxicillin for cough with phlegm

It is also believed that by the time breast cancer is confirmed, metastatic cancer cells have already been spread from liver lung on its way to brain.

Since all other organs including breast and liver could be removed and replaced by organ transplant except brain, I thought that protecting brain is utmost important to save life.

Once AZQ is developed to protect the brain, I could focus on the breast and prostate cancers.

Recent, radiolabeled studies showed that male hormone testosterone has

great

By attaching multiple aziridine rings and carbamate ions to both hormones, I could design novel drugs to attack the

breast

These mutations are caused by exposure to radiations, chemical or environmental pollutants, viral infection, or genetic inheritance.

To attack the mutated nucleotides among the 3000 cells in BRCA1 gene, I could use male hormone, testosterone, and bind multiple radiolabeled aziridine and carbamate ions to attack BRCA1 mutations. By using three-dimensional MRI, I could show how many radiolabeled nucleotides were bound to which mutations. Out of 17 positions available for substitutions on testosterone ring system, there are only three positions, that is, 1, 3, and 17 available for substitution on testosterone ring system.

Carl Djerassi [27] had demonstrated that we could activate positions 9 and 10 by reacting with bromoacetamide which introduces a bromo ion on position 10 which could be de-brominated by collidine to introduce a 9,10 double bond which we could further brominate to produce 9,10 dibromo compound. This bromo ion could be replaced by additional aziridine or carbamate ions. I could increase or decrease the number of aziridine and carbamate ions to get the maximum benefit by further brominating positions 15 and 16 to introduce additional aziridine and carbamate moieties.

Similarly, I could use

the

problem

What happens after we achieve that goal of reaching 100 years?

By exercises and good nutrition, if the body mass is

not

They need the help of caretakers to perform the daily routine.

By 2050, if we increase the age of about 100 years of about a billion people, we need another billion caretakers. The society is hardly likely to accept such a proposal.

To cure diseases to prolong human life, several present and future attempts are described below.

We need to make two rationale approaches: first, to identify rare allele in the genome of centenarians responsible for prolonging their lives. Once identified the allele, we need to conduct genetic engineering, that is, to cut, paste, copy, and splice the allele into the genome of volunteers to study its function. Second approach is to design drugs to shut off genes of old age to prolong life.

Next attempt to increase human life would be to prevent the loss of telomeres, the six-letter code (TTAGGG) that shorten our DNA and shorten our lifespan.

During replication, each chromosome loses about 30 telomeres each year.

If we prevent the loss of telomeres by using the enzyme telomerase reverse transcriptase (TRT), we could slow down the aging process. elegance that we could increase its lifespan several fold.

Now, we could translate this work in human being; we could try by making a less virulent flu virus carrying TRT gene when injected to a volunteer who comes down with a mild flu. When he recovers from the flu, the TRT gene would have inserted in the entire genome of every cell in his body (we can confirm the insertion by sequencing). Suppose at each replication, only 15 telomeres are deleted instead of 30 telomeres.

Also, suppose the sequencing of his genome would confirm that every cell of his body carries the TRT gene. Since the longevity treatment with the flu virus is safe, inexpensive, and would be easily available to everyone, should we provide the treatment to every man, woman, and child on the face of the Earth?

Such studies are likely to raise two serious ethical questions.

First, we have to ask ourselves, do people have a right to live and second do we have a right to live as long as we wish, no matter how old, how weak, or how sick we are?

The answer to first question is, according to the UN charter, we all have the right to life, liberty, and pursuit of happiness. Do people have a right to extent their lives as long as they wish?

Most people are reluctant to answer this question either No or Yes. First, they argue that there are seven and a half billion people live on planet Earth and we are adding 90 million additional people each year.

According to UN estimate, by 2050, the population of the world is likely to reach 9 billion.

Does our planet Earth have all resources to support such a population explosion? Can we provide food, fuel, and medicine to all the people of the world?

By extending life, we will have serious problems such as lawlessness, riots, and chaos in the streets. The current population of Earth has polluted the water, the air, and the land. Today, they wonder if the water they drink is safe, the food they eat is safe, and the air they breathe is safe. If we continue to pollute the planet with the current rate which is 110 million ton of pollutant that we release in the atmosphere each year, how much pollutants we would accumulate in the atmosphere in 10 years or in 100 years. On the other hand, those who say Yes; we should extend life have good reasons as well. We have no Plan B to save human life on some other planet. We look up to Heaven to find another home for humanity.

To search for a suitable planet for human life to

survive

We do not want them to die on their way to find a new home for humanity. We must continue to search for

treatment

Say the treatment is safe, inexpensive, and easily available to every man, woman, and child on the face of the Earth.

Who decide that person A will receive the longevity treatment and will live and person B will not receive the same treatment and therefore will die? We need debate and discussion and come up with guidelines for our society.

One person cannot provide answer to

all

My aim will be fulfilled if I have made you think along these lines.

Amoxicillin overused for

treatment

and

However, inappropriate choice of antibiotic was low for sinusitis (2.2%), otitis media (3.4%), chest

infections

The researchers said that more work was needed to look into the variation they found between practices. But they concluded: ‘Future antibiotic stewardship activities may focus on encouraging prescribers in

primary

'As diagnostic uncertainty is not uncommon when URTI is recorded as well as possibility of otitis media and otitis externa occurring

together

But he added: ‘Amoxicillin is not generally indicated for URTIs, so I was surprised at the high level of use for this condition.

‘Also, I was surprised that for otitis externa, there seemed to be no recorded use of topical treatments.’ He said some decision support was now being built into electronic health record systems, which should help choice of the

most

On improved antibiotic stewardship, Professor Majeed said system-wide approaches were important. ‘This would include for example, feedback of data on prescribing by CCGs to practices for specific infections and comparisons with other practices.’ Bookshelf. A service of the

National

Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Amoxicillin is one of the most commonly used antibiotics in the primary care setting.

It is an amino-penicillin, created by adding an extra amino group to penicillin, to battle antibiotic resistance. Amoxicillin covers a wide variety of gram-positive bacteria,

with

Similar to penicillin, it covers most Streptococcus species and has improved coverage of Listeria monocytogenes and Enterococcus .

It also has coverage over Haemophilus influenzae , some Escherichia coli , Actinomyces , Clostridial species, Salmonella , Shigella , and Corynebacteria .

Amoxicillin is FDA approved for the treatment of genitourinary tract infections, ear, nose, and throat infections, lower respiratory tract

infections

It is recommended as the first-line treatment by the Infectious Disease Society of America (IDSA), for acute bacterial rhinosinusitis and as one of the treatments for community-acquired pneumonia.[1] For this, it is often in combination with a macrolide antibiotic. The Centers for Disease Control and Prevention (CDC)

recommends

inhalation

It can be effective in periodontitis in combination with metronidazole and is one of the first-line treatments for group A streptococcus pharyngitis.

Amoxicillin is in the class of beta-lactam antibiotics.

Beta-lactams act by binding to penicillin-binding proteins that

inhibit

This process leads to lysis of the cell wall, and thus, the destruction of the bacterial cell. This type of activity is referred to as bactericidal killing.

Amoxicillin administration can also be in combination with a beta-lactamase inhibitor.

Some examples of these are clavulanic acid and sulbactam.

These beta-lactamase inhibitors

work

irreversibly

These drugs do not have inherent bactericidal activity; however, when coupled with amoxicillin, they may broaden spectrum amoxicillin to organisms that produce the penicillinase enzyme.[3] Administration.

Bactericidal antibiotics, such as amoxicillin, often are most effective in a “time-dependent” manner, rather than a “concentration-dependent” manner. Time-dependent refers to the time

that

Therefore, they are often dosed more frequently,

rather

The more “around-the-clock” dosing provides less variation in peak and trough serum levels. Amoxicillin is an oral antibiotic; whereas, ampicillin can be given orally, intravenously, or intramuscularly. Amoxicillin comes in immediate-release or extended-release tablets.

If given in suspension, it may be mixed and administered with formula, milk, water, fruit juice, ginger ale, or other cold drinks. Administration should take place immediately after mixing. Extended-release tablets should not be crushed, and the administration should be within 1 hour after finishing a meal. Amoxicillin is sometimes preferred over penicillin in children because of its taste.

It is important to note that it is excreted by in the majority of people by the kidney, and some renal adjustment and extra caution

may

It is reported to be partially dialyzable, and therefore, immediate-release tablets can be an option for dosing after hemodialysis.

There are no guidelines for hepatic dosing or geriatric dosing.