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Unlike penile implants, PotencyFlow® will not damage the penile erectile tissue and will therefore be preferred entry procedure especially for patients with some functionality left, having vascular problems. PotencyFlow® is intended to be controlled wirelessly or by a push button under the skin resulting in a smooth chain of events that is expected to lead to a more natural erect penis.

Surgical procedures to stop the vascular leak have been tried with good results, however, only in the short-term. After a year or two the venous blood system creates new paths expanding small vessels and the symptoms reoccur. However, with an intermittent and short-term closure, such as PotencyFlow®, one could expect this effect to be close to non-existent. Preventing the leak of the filling blood in the penis will create the possibility for these patients to achieve, and after being stimulated to get erection, keep the erection.

Implantica’s solution is walmart pharmacy sildenafil price expected to be able to help a much larger group of patients than those performing penile implants, due to its additive character. Wireless control is designed to enable activation of erection in a controlled and discrete way. PotencyFlow® is expected to temporarily restrict the blood flow and leave the corpus cavernosum undamaged – unlike current penile implants. Because PotencyFlow® method of treatment is designed to only be active during a short period of time, the risk of complications is likely reduced. Erectile Dysfunction (ED) can be defined as ‘the inability to achieve an erection satisfactory for sexual intercourse.

Satisfaction is determined by both patient and partner, making ED a ‘couple’s disease’. The degree of ED can range from a total inability to achieve an erection, an inconsistent ability to do so, or a tendency to sustain only brief erections. The World Health Organization specifies a three-month minimum duration of symptoms to establish the diagnosis.

Approximately 5% of 40-year-old men and 15-25% of 65-year old men suffer from complete ED. The penis has two chambers called the corpora cavernosa, which run the length of the organ and are filled with spongy tissue. The corpora

cavernosa

Impulses from the brain and local nerves cause the muscles of the corpora cavernosa to relax, which allows rapid blood flow to fill the spongy chambers, thus creating pressure in the corpora cavernosa and expanding the penis.

An erection is sustained when the tunica albuginea helps trap the blood within corpora cavernosa, but is reversed when the muscles in the penis contract, which stops the inflow of blood and opens the outflow channels.

Usually, oral drugs are the first step in ED treatment and are referred to as first line treatment. However, these drugs only treat 50% of a group of 150 million men. Penile injection has been used as a second line treatment for over a decade.

It has a higher success rate than drug treatment, but it is not generally considered a popular form of treatment with patients because of the need to administer regular self- injection into the corpora cavernosa of the penis.

Following urination, a small pellet is inserted approximately an inch deep into the urethra via an applicator at the tip of the penis. The method is just slightly easier to self-administer than injections and it also suffers from the lack of spontaneity. Patients generally have tried both drugs and other treatments before they are considered suitable for third line treatment. The use of drugs like Viagra and new competitors producing implants have caused a rapid increase in the use of penile implants. In some cases, surgery is used to repair damaged arteries and tie off veins.

The most common method is penile venous reconstructive surgery, also called venous ligation. This is a method used when the blood drains out too quickly through the veins.

If this occurs, the veins that drain the penis may be tied off, however, because new veins develop over 1-2 years time and again cause leakage of blood from the erected penis, this method has not been very successful in the long run. Penile prostheses for the treatment of ED have been available for more than 30 years in the US. A key discovery in the field of penile prosthetics was that the corpora cavernosa could be accessed surgically without damaging the penile vessels, urethra or sensory nerves. The most commonly used implants are multi-component inflatable implants, consisting of two or three components.

Inflatable cylinders placed in the corpora cavernosa, a fluid reservoir implanted in the abdomen or lower pelvis and a small pump placed in the scrotum.

The user squeezes the pump and fluid moves from the reservoir into the cylinders to create an erection. A further squeeze of the pump reverses the process. The main problem with penile implants is that the normal functionality is damaged permanently, meanwhile a devise like PotencyFlow® adds to your exiting functionality.

3 Belsley et al., 1998; Brooks & Jordan, 2001 4 Garber, walmart pharmacy sildenafil price 2005. Implantica is developing products generic viagra us pharmacy for the treatment of Erectile Dysfunction (ED).

The company is focused on high technology products which are designed to help patients attain a higher quality of life and provide benefits over current existing products by being easier to use and generally more acceptable to the patient population.

Formerly known as ‘impotence’, the term Erectile Dysfunction (ED) is now more often used to distinguish it from other problems related with sexual intercourse, e.g. lack of sexual desire or ejaculation and orgasm problems (Brooks & Jordan, 2001).

ED is treatable and not a life-threatening disease.

However, the condition may result in numerous social and personal problems: depression, withdrawal from sexual intimacy, marital problems, reduced quality of life, decreased working productivity, and increased healthcare utilization (Dhanani et al., 1998, cited by Joyce et al., 2007). With the introduction of Viagra in 1994, the market for erectile dysfunction treatments boomed. Still, many men hesitate to seek help due to the social stigma and embarrassment associated with ED.

Erectile Dysfunction was defined at the National Institutes of Health Consensus Conference in Washington DC, US, December 1992 as ‘the inability to achieve an erection satisfactory for sexual intercourse’ (National Institutes of Health, 1993).

Satisfaction is determined by both patient and partner, making ED a ‘couple’s disease’. The degree of ED can range from a total inability to achieve an erection, an inconsistent ability to do so, or a tendency to sustain only brief erections.

The World Health Organisation specifies a three-month minimum duration of symptoms to establish the diagnosis (WHO cited by Joyce et al., 2007).

Approximately 5 % of 40 year old men and 15-25 % of 65 year old men suffer from

complete