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If these drugs are being used at the same time as tadalafil, the dose of tadalafil should be reduced to 10 mg every 72 hours when used as needed or 2.5 mg when used daily in order to avoid side effects from high levels of tadalafil. Rifampin, carbamazepine (Tegretol, Tegretol XR, Equerto, Carbatrol), phenytoin (Dilantin, Dilantin-125), and phenobarbital may decrease blood levels of tadalafil, possibly reducing the effect of tadalafil. Tadalafil exaggerates the increases in heart rate and lowering of blood pressure caused by nitrates, for example, nitroglycerin, isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, Ismo, Monoket), nitroglycerin (Nitro-Dur, Transderm-Nitro) that are used primarily for treating heart pain (angina). In patients who take nitrates for angina, tadalafil could cause heart pain or possibly even a heart attack by exaggerating the increase in heart rate and the lowering of blood pressure. Therefore, tadalafil should not be used with nitrates. Tadalafil also exaggerates the blood pressure lowering effects of some alpha-blocking drugs for example, terazosin (Hytrin) that primarily are used for treating high blood generic viagra super active pressure or enlargement of the prostate (BPH). Individuals who take these alpha-blockers should be on a stable dose of the alpha-blocker before tadalafil is started. In such situations, tadalafil should be started at the lowest dose. If the patient is already taking tadalafil, the alpha-blocker should be started at the lowest dose. Combining tadalafil with alpha-blockers for treatment of BPH is not recommended. Therefore, combining tadalafil with alcohol may cause excessive drops in blood pressure and cause dizziness, headaches, and increased heart rate. PDE5 inhibitors may affect platelet function and therefore prolong bleeding. Tadalafil should be used cautiously in patients with bleeding disorders or active ulcers. Tadalafil should not be combined with Adcirca (another form of tadalafil) or other PDE5 inhibitors, for example, vardenafil (Levitra) or sildenafil (Viagra, Revatio). Viagra increases the effects of the blood pressure lowering medications. It also increases the blood pressure lowering effects of nitrates, for example, isosorbide dinitrate (Isordil), isosorbide mononitrate (Imdur, Ismo, Monoket), nitroglycerin (Nitro-Dur, Transderm-Nitro) that are used primarily for treating angina. Patients taking nitrates should not receive Viagra. Patients should not combine Viagra with other PDE5 inhibitors (for example, vardenafil [Levitra], tadalafil [Cialis]). Cimetidine (Tagamet), erythromycin, ketoconazole (Nizoral), itraconazole (Sporanox), atazanavir (Reyataz), and mibefradil (Posicor) can cause marked increases in the amount of Viagra in the body. Patients taking these medications should be observed carefully if sildenafil is used. It is expected that rifampin will decrease blood levels of Viagra and probably reduce its effectiveness. Are Cialis and Viagra safe to use while pregnant and breastfeeding? Tadalafil is not approved for women and has not been evaluated in women who are breastfeeding. Although extensive testing in animals has demonstrated no negative effects on the fetus, Viagra has not been studied in pregnant women. There is no effect on sperm count or motility of sperm in men. It is not known whether sildenafil is excreted into breast milk. Subscribe to MedicineNet's General Health Newsletter. By clicking Submit, I agree to the MedicineNet's Terms & Conditions & Privacy Policy and understand that I may opt out of MedicineNet's subscriptions at any time. Cialis (tadalafil) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Learn about erectile dysfunction causes and treatments such as drugs. Enlarged Prostate (BPH) Symptoms, Diagnosis, Treatment. Benign Prostatic Hyperplasia (BPH) is a condition cause by an enlarged prostate. Here we explore how stress, lack of sleep, weight gain, depression and low T can. Learn sex tips for men that lead to more sexual pleasure such as better communication, focusing on pleasurable sensations. Learn how to overcome common health conditions affecting those over 50 such as. Benign Prostatic Hyperplasia (Enlarged Prostate) Quiz. Take the Enlarge Prostate Quiz and challenge your knowledge of prostate problems. Erectile Dysfunction (Impotence) Quiz: Causes & Treatment. Did you know that certain medical condition may be responsible for ED? Some causes of impotence are medically treatable and. Male sexual dysfunction can be caused by physical or psychological problems. Common sexual problems in men include erectile dysfunction (impotence or ED), premature ejaculation, and loss of libido. Treatment for sexual dysfunction in men may involve medication, hormone therapy, psychological therapy, and the use of mechanical aids. Enlarged Prostate (BPH, Benign Prostatic Hyperplasia) Benign prostatic hyperplasia (BPH or enlarged prostate) is very common in men over 50 years of age. Half of all men over the age of 50 develop symptoms of BPH, but few need medical treatment. This noncancerous enlargement of the prostate can impede urine flow, slow the flow of urine, create the urge to urinate frequently and cause other symptoms like complete blockage of urine and urinary tract infections. More serious symptoms are urinary tract infections (UTIs) and complete blockage of the urethra, which may be a medical emergency. Not all men with the condition need treatment, and usually is closely monitored if no symptoms are present. Treatment measures usually are reserved for men with significant symptoms, and can include medications, surgery, microwave therapy, and laser procedures. Men can prevent prostate problems by having regular medical checkups that include a prostate exam. BPH (Enlarged Prostate) Differences kroger viagra and Similarities. Prostatitis and BPH (benign prostatic hyperplasia, enlarged prostate gland) are both conditions of the prostate gland. There are four types of prostatitis that can be caused by infections (usually bacterial) or other health conditions or problems, acute bacterial prostatitis (type I), chronic bacterial prostatitis (type II), chronic prostatitis and chronic pelvic pain syndrome (type III), and asymptomatic inflammatory prostatitis (type IV). BPH is inflammation of the prostate gland, and most men have the condition by age 50. Doctor's don't know what causes this inflammation, but they theorize that it may be related to hormones. Both of these conditions can cause similar symptoms like low back pain, pain during urination, or difficulty or the inability to urinate. However, prostatitis has many more symptoms and signs than BPH, and they based on the type of prostatitis. Examples include low back pain and/or abdominal pain, painful urination, fever, chills, feeling tired, recurrent urinary tract infections (UTIs), painful urination intermittently, intermittent obstruction urinary tract symptoms (frequent, painful, or incomplete urination), pelvic pain and/or discomfort, pain with ejaculation, and erectile dysfunction (ED). If you think you have either of these conditions contact your doctor or other health care professional. Bacterial prostatitis can be cured with antibiotics; however, there is no cure for BPH. Erectile Dysfunction (ED, Impotence) Erectile dysfunction (ED, impotence) is the failure to achieve or maintain an erection. There are many potential underlying causes of erectile dysfunction, including stress and emotional problems, brain dysfunction, problems with blood supply to the penis, and structural problems with the penis. Erectile dysfunction is diagnosed by taking the patient's history and physical exam. Blood tests measuring kidney function and blood sugar, cholesterol, hormone, and prostate-specific antigen (PSA) levels may be ordered. Urinalysis, ultrasound, and other more sophisticated tests may be required. The treatment of erectile dysfunction depends on the underlying cause. Medications, penile injections, penile implants, and vacuum devices may be used. Treatment for erectile dysfunction is usually successful. The patient should manage heart disease risk factors (high blood pressure, high cholesterol, diabetes) as they are related to erectile dysfunction risk. Having diabetes can mean early onset and increased severity of bladder symptoms (urinary incontinence and urinary tract infections) and changes in sexual function. Men may have erectile dysfunction; and women may have problems with sexual response and vaginal lubrication. Keep your diabetes under control, and you can lower your risk of sexual and urologic problems. Sexual health information including birth control, impotence, herpes, sexually transmitted diseases, staying healthy, women's sexual health concerns, and men's sexual health concerns. Learn about the most common sexual conditions affecting men and women. Cialis vs Viagra - What's the difference between them? Cialis and Viagra are both PDE5 inhibitors used for the treatment of erectile dysfunction (ED). Cialis lasts for around 36 hours compared with only 4 to 5 hours for Viagra. Food does not affect the activity of Cialis, whereas food may decrease the effectiveness of Viagra. Cialis can be used once daily, at a smaller dosage, and is also effective at treating benign prostatic hyperplasia (BPH). Dosage of Cialis may need to be reduced in men with liver or kidney problems and risk of interactions may be higher than with Viagra. What ingredients are contained in Cialis or Viagra and how do they work? Cialis is the brand name for tadalafil and Viagra is the brand name for sildenafil. 1,2 Both belong to a class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors. PDE5 inhibitors work only in the presence of sexual stimulation, as they rely on the natural release of nitric oxide (NO), a chemical only released during sexual arousal. NO in turn activates other substances to relax the smooth muscle inside the penis to allow the inflow of blood and an erection to occur. Which drug was first approved and which one lasts for longer? On March 27 th , 1998, Viagra became the first oral pill, and the first PDE5 inhibitor, to be approved by the FDA to treat ED. 4 A generic for Viagra was approved in March 2016 5 and released in December 2017. Cialis was first approved for ED on November 21st, 2003. 6 It was the third PDE5 inhibitor to come onto the market (after Levitra [vardenafil]). 7 Cialis has an advantage over Viagra and Levitra in that it lasts for a lot longer – 36 hours, compared with 4-5 hours for Viagra and Levitra. 1,2,7 A generic for Cialis was approved in May 2018 11 and released in September 2018. How quickly do Cialis and Viagra work and does food have any effect. Cialis generally works within 16 to 45 minutes, and its activity is not affected by food. Viagra generally works within 30 minutes, and its effect may be diminished if taken soon after a high fat meal (which may also delay how fast it works). For this reason, Viagra is best taken on an empty stomach. Effectiveness of all PDE5 inhibitors is similar; although reported effectiveness of Viagra, at 84% is slightly higher than that of Cialis at 81%. 7 However, more men prefer Cialis because of its longer duration of effect. Cialis can be taken on an as needed basis, or daily. 1 Generally, daily dosages are smaller than as needed doses. 8 Typically, Cialis is taken as a 10mg starting dose, prior to sexual activity. The dosage may be increased to 20mg if 10mg is ineffective or reduced to 5mg if side effects are intolerable. When Cialis is taken for daily use, the recommended initial dosage is 2.5mg once daily, or 5mg for people who also have BPH. Timing of the daily dosage does not matter in people using it solely for ED; however, those with BPH are advised to take it at the same time each day. Do not take more than one dose a day but your doctor may consider an increase in dosage from 2.5 to 5mg if ineffective. Side effects of Cialis include headache and indigestion. Viagra is taken on an as needed basis, at a dose of 50mg, approximately 1 hour before sexual activity (although can be taken from 30 minutes to 4 hours before). The dose may be increased to 100mg if 50mg is ineffective or decreased to 25mg if side effects are intolerable. 2 Viagra should only be taken once a day even though the effects wear off after approximately 4-5 hours. The main side effects are headache, flushing and indigestion. 2 Rarely, color perception may be altered with Viagra. Cost of Viagra varies depending on tablet strength but is approximately $24 per tablet for the 50mg strength and $35 for the 100mg strength. 9 Cialis costs approximately $8.50 for the 5mg strength and $28 for the 20mg strength, per tablet. All PDE5 inhibitors are contraindicated with nitrates. 1,2 The longer duration of action of Cialis means it is at higher risk for drug interactions, 1 and dosages may need reducing in men with kidney or liver disease. Cialis is not recommended in men who have had a heart attack or stroke within the past 6 months, with either uncontrolled high blood pressure or severely low blood pressure, unstable angina, or other conditions that make sexual activity inadvisable. Erections aren’t always easy for millions of men in the UK. Choose from highly effective, clinically proven solutions. Sildenafil is the active ingredient in both branded Viagra and generic Sildenafil tablets. Sildenafil and Viagra are PDE5 inhibitors, meaning they work by allowing blood vessels to expand and relax. This increases the blood flow to the penis, making it easier to get – and maintain – an erection, thus improving sexual performance for men who are suffering from erectile dysfunction (ED). Sildenafil and Viagra work the same; they’re equally effective, require the same amount of time to take effect, and they work for the same duration. The main difference between Sildenafil and Viagra is the branding and the price. Viagra tablets inevitably cost more than the generic Sildenafil medication. When researching your options for erectile dysfunction medications, the huge variety of brands on the market can be a pain to navigate. Finding the right medication shouldn’t be a big deal – millions of men suffer with ED, and you’re simply looking for the best option. While there are other branded and generic types of ED medications available, such as Tadalafil, Cialis, Levitra, Avanafil and Spedra – Viagra is still the most famous. This is thanks to Viagra being the first solution widely available for assisting men with ED – not to mention its clever marketing over the years. As a result of becoming a household name, Viagra is expected to keep a 29% market share by 2022. The less-catchy name might give you reason to pause, but hear us out. Like Viagra, Sildenafil has a high rate of success – whatever the underlying reasons behind your ED. In this article, we’ll try to give you the kroger viagra key info you need to choose between Viagra and Sildenafil. What Are the Similarities Between Viagra and Sildenafil? Plainly speaking, Sildenafil and Viagra are the same medication and contain the same active ingredient. Sildenafil is the generic or unbranded version, and Viagra is the globally famous “little blue pill” brand. Though it may seem like Sildenafil is the newbie ED medication, there are no real solid reasons to prefer the more established Viagra product over Sildenafil. Sildenafil was invented back in the late 1980s by scientists working for American pharmaceutical company, Pfizer. The medication was initially developed to treat heart problems like angina, but was patented by Pfizer in 1998 as Viagra once they’d realised its potential as a licensed ED medication. Pfizer’s patent for Viagra expired in 2012 for countries outside the US, and it expires completely in 2020. This means that generic forms of the same medication, known simply as Sildenafil, can enter the market. Both drugs have the same amount of active ingredient (Sildenafil Citrate) in each comparable dose. In medical terms, this is known as bioequivalence . Importantly for you, this means the way both drugs work, how long they take to work, how well they work and how long they work for, are the same. Despite its notoriety, Viagra is not “better” than Sildenafil or another branded product. They have the same effect on your ability to maintain an erection. Important note: The bioequivalence also means you need to steer clear of both Sildenafil and Viagra if you have been medically advised against taking either of them. Sildenafil and Viagra both work by inhibiting the PDE5 enzyme, which controls muscle contraction in the penis. The drug allows the blood vessels in the penis to relax and expand, boosting the blood flow to the area and making it easier to maintain a lasting erection. It is beneficial to be sexually aroused for both medications to work effectively, so you’ll need to get in the mood, relax, and let the pill do its thing! MHRA approved and clinically proven to be highly effective by increasing blood flow into the penis. Viagra, Cialis, Levitra, and Stendra are oral medications used to treat erectile dysfunction (ED). You may also know them by their generic names: sildenafil (Viagra) tadalafil (Cialis) vardenafil (Levitra) avanafil (Stendra) About 30 million American men occasionally have a problem with getting or keeping an erection, according to the Urology Care Foundation. When ED becomes a problem, many men turn to these oral ED medications. However, there are also viagra 50mg tablet online shopping some key differences, such as when you take them, how long they work, and what their side effects are. Viagra, Cialis, Levitra, and Stendra are all in a class of drugs called PDE5 inhibitors. These drugs work by blocking an enzyme called phosphodiesterase type 5. They also boost a chemical in your body called nitric oxide. This action encourages the muscles in your penis to relax. Relaxed muscles allow blood to flow freely so that when you’re aroused, you can get an erection. It also helps you maintain the erection long enough to have sex. Here are the basic features of each of these drugs: Brand name Viagra Cialis Levitra Stendra What’s the generic name of this drug? sildenafil tadalafil vardenafil avanafil Is a generic version available? oral tablet oral tablet oral tablet oral tablet What strengths does it come in? 25 mg, 50 mg, 100 mg 2.5 mg, 5 mg, 10 mg, 20 mg 5 mg, 10 mg, 20 mg 50 mg, 100 mg, 200 mg What’s the typical dosage? 50 mg 10 mg (when used as needed); 2.5 mg (when used daily) 10 mg; 5 mg (for men 65 years old and up) 100 mg When do I take it? 30-60 minutes before sex 30 minutes before sex 60 minutes before sex 15 minutes before sex (for 100 mg and 200 mg); 30 minutes before sex (for 50 mg) How long does it work? 4 hours up to 36 hours 4-5 hours 6 hours How do I store it? Around room temperature, between 68°F to 77°F (20°C to 25°C) At 25°C (77°F) At 25°C (77°F) Around room temperature, between 68°F to 77°F (20°C to 25°C) The drugs are available in a variety of doses, ranging from 2.5 milligrams (mg) to 200 mg. However, taking these drugs after eating a high-fat meal does slow the rate of absorption. Most of them stay in your bloodstream for about four to five hours. Cialis is the exception, as it remains in your bloodstream for up to 36 hours. The length of time a drug stays in your system may be important if you’re taking other medications. You shouldn’t take any of these drugs more than once in a 24-hour period. Viagra, Cialis, Levitra, and Stendra are usually stocked at most pharmacies. In general, most health insurance companies won’t cover their costs. However, if you have certain medical conditions, your health plan may pay for the drug with prior authorization. The exact price you pay for any drug will depend on your insurance plan and your pharmacy. Generic versions of Viagra, Cialis, Levitra can cost half as much as their brand-name counterparts, if not less. The side effects of these medications are mostly similar. Below are the drugs’ most common side effects, according to their manufacturers: Side effect Viagra Cialis Levitra Stendra Stuffy or runny nose x x x x Headache x x x x Dizziness x x Upset stomach x x x Nausea x Indigestion x x Vision changes x Rash x Flushing x x x x Back pain x x x x Pain in the limbs x Muscle aches x x Sore throat x. Tell your doctor if you have any side effects that linger and don’t go away on their own. If you have an erection that lasts longer than four hours, call your doctor right away. This condition, known as priapism, is a risk associated with all of these ED drugs. Unlike Viagra and the other PDE5 inhibitors, Cialis is also approved to treat enlarged prostate. Both Viagra and Cialis can be taken 30 minutes before sexual activity. However, Cialis lasts much longer and is noteworthy for the amount of time it remains in your body. You may feel the effects of the drug up to 36 hours after you take it. The fact that it comes in a low-dose (2.5 mg) version also means that Cialis can be taken every day. A daily dose will ensure that the drug’s always in your system. This side effect isn’t associated with any other oral ED drugs. Viagra can take 30 to 60 minutes to work in the body, while Levitra takes 60 minutes. Levitra does have fewer common side effects than Viagra, and it isn’t associated with a rash or muscle aches. While vision changes are considered a common side effect of Viagra, changes to color perception are only a rare side effect of Levitra. Stendra is the newest drug on the market, and no generic version is available for sale yet.
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