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There may be some men for whom medication is unsuitable, either because of other medical conditions or another reason. In these situations, other medical treatments may be suggested. Vacuum erection devices are hollow tubes also known as penis pumps. They are attached to a hand- or battery-operated pump and work by drawing blood into the penis. They help a man to achieve an erection that he can maintain using a tension ring. Implants are inflatable or bendable rods that are surgically implanted into the erection chambers of the penis. Doctors will usually only recommend this type of treatment as a last resort. A qualified healthcare professional must deliver these treatments. Several dietary supplements, herbal preparations, and food products are sold as remedies for erectile dysfunction. Some alternative herbal treatments, which have shown positive results in small studies, are also available. Some herbs that are generally considered to be safe and are available to purchase online include: However, be careful when purchasing or consuming any alternative products, including those that claim to be herbal versions of Viagra. Food and Drug Administration (FDA) has issued several statements warning consumers about the safety of such goods. They say these products may contain hidden synthetic chemicals or other ingredients that could be harmful. There has not been enough research to support the usage of these supplements fully. According to the FDA, lab tests show that nearly 300 of the supplements or foods marketed to enhance sexual function contain undisclosed drug ingredients. Any person using a supplement must let their doctor know. Herbs are not monitored by the FDA for quality or purity. Choose your brand/products after doing research on the company. Cialis vs Viagra - What's the difference between them? Cialis and Viagra are both PDE5 inhibitors used for the treatment of erectile dysfunction (ED). Cialis lasts for around 36 hours compared with only 4 to 5 hours for Viagra. Food does not affect the activity of Cialis, whereas food may decrease the effectiveness of Viagra. Cialis can be used once daily, at a smaller dosage, and is also effective at treating benign prostatic hyperplasia (BPH). Dosage of Cialis may need to be reduced in men with liver or kidney problems and risk of interactions may be higher than with Viagra. What ingredients are contained in Cialis or Viagra and how do they work? Cialis is the brand name for tadalafil and Viagra is the brand name for sildenafil. 1,2 Both belong to a class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors. PDE5 inhibitors work only in the presence of sexual stimulation, as they rely on the natural release of nitric oxide (NO), a chemical only released during sexual arousal. NO in turn activates other substances to relax the smooth muscle inside the penis to allow the inflow of blood and an erection to occur. Which drug was first approved and which one lasts for longer? On March 27 th , 1998, Viagra became the first oral pill, and the first PDE5 inhibitor, to be approved by the FDA to treat ED. 4 A generic for Viagra was approved in March 2016 5 and released in December 2017. Cialis was first approved for ED on November 21st, 2003. 6 It was the third PDE5 inhibitor to come onto the market (after Levitra [vardenafil]). 7 Cialis has an advantage over Viagra and Levitra in that it lasts for a lot longer – 36 hours, compared with 4-5 hours for Viagra and Levitra. 1,2,7 A generic for Cialis was approved in May 2018 11 and released in September 2018. How quickly do Cialis and Viagra work and does food have any effect. Cialis generally works within 16 to 45 minutes, and its activity is not affected by food. Viagra generally works within 30 minutes, and its effect may be diminished if taken soon after a high fat meal (which may also delay how fast it works). For this reason, Viagra is best taken on an empty stomach. Effectiveness of all PDE5 inhibitors is similar; although reported effectiveness of Viagra, at 84% is slightly higher than that of Cialis at 81%. 7 However, more men prefer Cialis because of its longer duration of effect. Cialis can be taken on an as needed basis, or daily. 1 Generally, daily dosages are smaller than as needed doses. 8 Typically, Cialis is taken as a 10mg starting dose, prior to sexual activity. The dosage may be increased to 20mg if 10mg is ineffective or reduced to 5mg if side effects are intolerable. When Cialis is taken for daily use, the recommended initial dosage is 2.5mg once daily, or 5mg for people who also have BPH. Timing of the daily dosage does not matter in people using it solely for ED; however, those with BPH are advised to take it at the same time each day. Do not take more than one dose a day but your doctor may consider an increase in dosage from 2.5 to 5mg if ineffective. Side effects of Cialis include headache and indigestion. Viagra is taken on an as needed basis, at a dose of 50mg, approximately 1 hour before sexual activity (although can be taken from 30 minutes to 4 hours before). The dose may be increased to 100mg if 50mg is ineffective or decreased to 25mg if side effects are intolerable. 2 Viagra should only be taken once a day even though the effects wear off after approximately 4-5 hours. The main side effects are headache, flushing and indigestion. 2 Rarely, color perception may be altered with Viagra. Cost of Viagra varies depending on tablet strength but is approximately $24 per tablet for the 50mg strength and $35 for the 100mg strength. 9 Cialis costs approximately $8.50 for the 5mg strength and $28 for the 20mg strength, per tablet. All PDE5 inhibitors are contraindicated with nitrates. 1,2 The longer duration of action of Cialis means it is at higher risk for drug interactions, 1 and dosages may need reducing in men with kidney or liver disease. Cialis is not recommended in men who have had a heart attack or stroke within the past 6 months, with either uncontrolled high blood pressure or severely low blood pressure, unstable angina, or other conditions that make sexual activity inadvisable. Viagra, Cialis, Levitra, and Stendra are oral medications used to treat erectile dysfunction (ED). You may also know them by their generic names: sildenafil (Viagra) tadalafil (Cialis) vardenafil (Levitra) avanafil (Stendra) About 30 million American men occasionally have a problem with getting or keeping an erection, according to the Urology Care Foundation. When ED becomes a problem, many men turn to these oral ED medications. However, there are also some key differences, such as when you take them, how long they work, and what their side effects are. Viagra, Cialis, Levitra, and Stendra are all in a class of drugs called PDE5 inhibitors. These drugs work by blocking an enzyme called phosphodiesterase type 5. They also boost a chemical in your body called nitric oxide. This action encourages the muscles in your penis to relax. Relaxed muscles allow blood to flow freely so that when you’re aroused, you can get an erection. It also helps you maintain the erection long enough to have sex. Here are the basic features of each of these drugs: Brand name Viagra Cialis Levitra Stendra What’s the generic name of this drug? sildenafil tadalafil vardenafil avanafil Is a generic version available? oral tablet oral tablet oral tablet oral tablet What strengths does it come in? 25 mg, 50 mg, 100 mg 2.5 mg, 5 mg, 10 mg, 20 mg 5 mg, 10 mg, 20 mg 50 mg, 100 mg, 200 mg What’s the typical dosage? 50 mg 10 mg (when used as needed); 2.5 mg (when used daily) 10 mg; 5 mg (for men 65 years old and up) 100 mg When do I take it? 30-60 minutes before sex 30 minutes before sex 60 minutes before sex 15 minutes before sex (for 100 mg and 200 mg); 30 minutes before sex (for 50 mg) How long does it work? 4 hours up to 36 hours 4-5 hours 6 hours How do I store it? Around room temperature, between 68°F to 77°F (20°C to 25°C) At 25°C (77°F) At 25°C (77°F) Around room temperature, between 68°F to 77°F (20°C to 25°C) The drugs are available in a variety of doses, ranging from 2.5 milligrams (mg) to 200 mg. However, taking these drugs after eating a high-fat meal does slow the rate of absorption. Most of them stay in your bloodstream for about four to five hours. Cialis is the exception, as it remains in your bloodstream for up to 36 hours. The length of time a drug stays in your system may be important if you’re taking other medications. You shouldn’t take any of these drugs more than once in a 24-hour period. Viagra, Cialis, Levitra, and Stendra are usually stocked at most pharmacies. In general, most health insurance companies won’t cover their costs. However, if you have certain medical conditions, your health plan may pay for the drug with prior authorization. The exact price you pay for any drug will depend on your insurance plan and your pharmacy. Generic versions of Viagra, Cialis, Levitra can cost half as much as their brand-name counterparts, if not less. The side effects of these medications are mostly similar. Below are the drugs’ most common side effects, according to their manufacturers: Side effect Viagra Cialis Levitra Stendra Stuffy or runny nose x x x x Headache x x x x Dizziness x x Upset stomach x x x Nausea x Indigestion x x Vision changes x Rash x Flushing x x x x Back pain x x x x Pain in the limbs x Muscle aches x x Sore throat x. Tell your doctor if you have any side effects that linger and don’t go away on their own. If you have an erection that lasts longer than four hours, call your doctor right away. This condition, known as priapism, is a risk associated with all of these ED drugs. Unlike Viagra and the other PDE5 inhibitors, Cialis is also approved to treat enlarged prostate. Both Viagra and Cialis can be taken 30 minutes before sexual activity. However, Cialis lasts much longer and is noteworthy for the amount of time it remains in your body. You may feel the effects of the drug up to 36 hours after you take it. The fact that it comes in a low-dose (2.5 mg) version also means that Cialis can be taken every day. A daily dose will ensure that the drug’s always in your system. This side effect isn’t associated with any other oral ED drugs. Viagra can take 30 to 60 minutes to work in the body, while Levitra takes 60 minutes. Levitra does have fewer common side effects than Viagra, and it isn’t associated with a rash or muscle aches. While vision changes are considered a common side effect of Viagra, changes to color perception are only a rare side effect of Levitra.
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