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increasing or reducing the effectiveness of other drugs increasing toxicity by reducing the body’s ability to excrete the drug after use.

Amoxicillin can also affect the results of certain diagnostic tests, such as urine glucose tests. Doctors and other health care providers must be fully informed of any other drugs, treatments or tests that a patient is being given before they prescribe amoxicillin.

They may need to change the dosage or take extra precautions. Anyone who takes an overdose should call their local poison center at 1-800-222-1222. Amoxicillin may reduce the effectiveness of birth control measures, such as patches, rings, or the birth control pill. A secondary prevention method such as condoms may be needed during the treatment course.

Anyone who is using these methods of birth control should discuss their options with their physician or health care provider.

Although amoxicillin can treat certain infections effectively, repeated use can reduce its effectiveness. A 20-year study published in the BMJ in 2014 found that 1 in 10 of all antibiotic prescriptions failed to treat the infection.

This would appear to indicate a growing tendency toward antibiotic resistance, where overuse of antibiotics is reducing their effectiveness.

For this reason, doctors need to be sure that the patient’s condition is caused by a bacteria, and to know if a patient has previously used amoxicillin.

Alcohol does not affect the antibiotic activity of amoxicillin, but patients should avoid drinking alcohol while an active infection is present.

This can support the body in effectively eradicating infection.

The use of alcohol may also mask side effects that can occur with amoxicillin, increasing the potential for complications.

Health care providers should also know if the patient has any of the following conditions: allergy to penicillin or cephalosporin antibiotics asthma hay fever hives kidney disease mononucleosis phenylketonuria.

Being clear and concise with doctors and health care providers will ensure the safe and effective use of amoxicillin. Amoxicillin is used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin. It is also used in combination with other medications to

eliminate

H. Amoxicillin is in a class of medications called penicillin-like antibiotics. Antibiotics such as amoxicillin will not work for colds, flu, and other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Amoxicillin comes as a capsule, a tablet, a chewable tablet, and as a suspension (liquid) to take by mouth.

It is usually taken every 12 hours (twice a day) or every 8 hours (three times a day) with or without food. The length of your treatment depends on the type of infection that you have. Take amoxicillin at around the same times every day.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well before each use to mix the medication evenly.

The suspension may be placed directly on the child's tongue or added to formula, milk, fruit juice, water, ginger ale, or another cold liquid and taken immediately. The chewable tablets should be crushed or chewed thoroughly before they are swallowed. Swallow the tablets and capsules whole with a full glass of water; do not chew or crush them. You should begin to feel better during the first few days of treatment with amoxicillin. If your symptoms do not improve or get worse, call your doctor. Take amoxicillin until you finish the prescription, even if you feel better.

If you stop taking amoxicillin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. Amoxicillin also is sometimes used to treat Lyme disease, to prevent anthrax infection after exposure, and to treat anthrax infection of the skin . Talk with your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking amoxicillin, tell your doctor and pharmacist if you are allergic to amoxicillin; penicillin antibiotics; cephalosporin antibiotics such as cefaclor, cefadroxil, cefazolin (Ancef, Kefzol), cefepime (Maxipime), cefixime (Suprax), cefotaxime (Claforan), cefotetan, cefoxitin (Mefoxin), cefpodoxime, cefprozil, ceftaroline (Teflaro), ceftazidime (Fortaz, Tazicef, in Avycaz), ceftibuten, ceftriaxone, cefuroxime (Ceftin, Zinacef), and cephalexin (Keflex); any other medications; or any of the ingredients in amoxicillin capsules, tablets, or suspension. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: allopurinol (Lopurin, Zyloprim), other antibiotics, anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), oral contraceptives,

and

probenecid (Probalan, in Col-Probenecid).

Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if

you

have mononucleosis (a virus; also called 'mono') and if you have or have ever had kidney disease, allergies, asthma, hay fever, or hives.

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking amoxicillin, call your doctor.

if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that some amoxicillin chewable tablets are sweetened with aspartame that forms phenylalanine. Unless your doctor tells you otherwise, continue your normal diet. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.

Do not take a double dose to make up for a missed one. Tell your doctor if any of these symptoms are severe or do not go away:

nausea

vomiting diarrhea changes in taste headache. If you experience any of these symptoms, stop taking amoxicillin and

call

your doctor immediately or get emergency medical treatment: rash skin blisters or peeling itching hives wheezing difficulty swallowing or breathing swelling of the face, throat, tongue, lips, and eyes severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment) Amoxicillin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).



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