19.03.2018
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Asian countries have the largest burdens of drug-resistant strains worldwide [ 4 Porter G, Grills N. Medication misuse in India: A major public health issue in India. [http://dx.doi.org/10.1093/pubmed/fdv072] [PMID: 26060236] ]. Furthermore, India is one of the major consumers of antibiotics in the world and their overuse and misuse are rambling [ 4 Porter G, Grills N. Medication misuse in India: A major public health issue in India. [http://dx.doi.org/10.1093/pubmed/fdv072] [PMID: 26060236] ]. Besides, India is at one of the top rates of resistance against antimicrobials that are used for the treatment of humans and farm animals [ 5 Van Boeckel TP, Brower C, Gilbert M, et al. Global trends in antimicrobial use in food animals. [http://dx.doi.org/10.1073/pnas.1503141112] [PMID: 25792457] ]. Currently, antibiotics are also utilizing against the treatment of several species of fungi and protozoans infections, but the impact of these is very toxic to humans and animals [ 6 Waksman SA. Antibiotics' effectiveness and easy access can lead to overuse or misuse prompting to develop resistance in microorganisms. In addition, inappropriate antibiotic dosages have also contributed to the emergence of antibiotic-resistant bacterial strains [ 7 Lewis R. Unappropriated practices of antibiotics have long been believed to fuel AMR, but newer research showed that simply lowering consumption is not enough [ 8 Cunha CB. Antimicrobial stewardship programs: Principles and practice. [http://dx.doi.org/10.1016/j.mcna.2018.04.003] [PMID: 30126571] ]. Significant problems are arising due to the development of antibiotic-resistant strains of bacteria and further creation of multidrug-resistant bacterial spp [ 9 Magiorakos AP, Srinivasan A, Carey RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance. [http://dx.doi.org/10.1111/j.1469-0691.2011.03570.x] [PMID: 21793988] ]. The multidrug-resistant bacterial spp., having resistance to multiple antibiotics, can cause life-threatening infections [ 10 Bassetti M, Righi E. For example, overuse of fluoroquinolone and other associated antibiotics can also lead to such kind of antibiotic resistance in bacteria [ 11 Fair RJ, Tor Y. Antibiotics and bacterial resistance in the 21st century. Developments of superbugs are the result of such kinds of antibiotic associated evils [ 12 Alpert PT. Superbugs: antibiotic resistance is becoming a major public health concern. In addition, few antibiotics have been associated with adverse side effects, including mild to very serious symptoms that depend upon treated microbial sps and individual patients [ 13 Torok E, Moran E, Cooke F. Oxford handbook of infectious diseases and microbiology 2016. [http://dx.doi.org/10.1093/med/9780199671328.001.0001] ]. The antibiotics can sometimes alter the host microbiota and lead to chronic infection and inflammation [ 14 Langdon A, Crook N, Dantas G. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. [http://dx.doi.org/10.1186/s13073-016-0294-z] [PMID: 27074706] ]. Usually, antibiotics side-effects are fever, nausea and major allergic reactions, including photo-dermatitis and anaphylaxis. The common side-effect of antibiotics is diarrhea, due to the misbalancing of the intestinal flora species or overgrowth of pathogenic bacteria [ 15 Bhattacharya S. Additional side-effects included the interaction with other drugs, such as the elevated risk of damage of tendon when quinolone antibiotic is given with a corticosteroid [ 16 Lewis T, Cook J. Fluoroquinolones and tendinopathy: A guide for athletes and sports clinicians and a systematic review of the literature. [http://dx.doi.org/10.4085/1062-6050-49.2.09] [PMID: 24762232] ]. The overuse of fluoroquinolone and other antibiotics leads to antibiotic resistance in bacteria, which might inhibit the treatment of antibiotic-resistant infections [ 16 Lewis T, Cook J. Fluoroquinolones and tendinopathy: A guide for athletes and sports clinicians and a systematic review of the literature. [http://dx.doi.org/10.4085/1062-6050-49.2.09] [PMID: 24762232] ]. The article summarizes the adverse effect of antibiotics, mechanisms of resistance, challenges and future strategies to combat antimicrobial resistance to manage the health care system. A side effect of antibiotics is a reaction that occurs in the patients, along with the therapeutic action [ 17 Heta S, Robo I. The side effects of the most commonly used group of antibiotics in periodontal treatments. [http://dx.doi.org/10.3390/medsci6010006] [PMID: 30720776] ]. If the dosage of antibiotics is used appropriately, antibiotics are relatively safe, with very few side effects. However, these side effects can range from mild allergic reactions to severe adverse, which may be extremely variable from patient to patient and from antibiotic to antibiotic [ 18 Thong BYH. [http://dx.doi.org/10.4168/aair.2010.2.2.77] [PMID: 20358021] ]. Moreover, many antibiotics may interfere with the individual patient’s ability to tolerate and complete the course [ 19 Saradamma RD, Higginbotham N, Nichter M. Social factors influencing the acquisition of antibiotics without prescription in Kerala State, south India. [http://dx.doi.org/10.1016/S0277-9536(99)00380-9] [PMID: 10695985] ]. Fewer patients having any previous allergic reaction to any kind of antibiotics are not recommended for the same. The allergic reactions may include symptoms like a skin rash and allergic reactions, called anaphylaxis, which can lead to difficulties in breath and swelling of the lips or tongue and face. Here, the common side-effects of major antibiotics are given below [ 20 Warrington RJ, McPhillips S. Independent anaphylaxis to cefazolin without allergy to other ?-lactam antibiotics. [http://dx.doi.org/10.1016/S0091-6749(96)70171-9] [PMID: 8757224] ]. (1) Penicillin: Rash, diarrhea, abdominal pain, nausea/ vomiting, drug fever, hypersensitivity (allergic) reactions, etc . Allergic reactions to drugs: Implications for perioperative care. [http://dx.doi.org/10.1053/jpan.2002.36669] [PMID: 12476405] ]. (2) Cephalosporin: Diarrhea, nausea/vomiting, hypersensitivity reactions, serum sickness, etc . Adverse events associated with the use of oral cephalosporins/cephems. Diagn Microbiol Infect Dis 2007; 57(3)(Suppl.): 67S-76S. [http://dx.doi.org/10.1016/j.diagmicrobio.2006.12.002] [PMID: 17292575] ]. (3) Aminoglycosides: Nausea/vomiting, nystagmus, etc . [http://dx.doi.org/10.1080/00325481.1978.11714923] [PMID: 704499] ]. (4) Erythromycin, azithromycin, clarithromycin: abdominal pain, diarrhea, anorexia, nausea/vomiting, taste alterations, etc . (5) Tetracycline: Nausea/vomiting, diarrhea, anorexia, abdominal pain, tooth discoloration in children 25 Greer ND. Tigecycline (Tygacil): the first in the glycylcycline class of antibiotics. Baylor University Medical Center Proceedings 2006; 19(2): 155-61. (6) Quinolones ciprofloxacin (cipro), levofloxacin (levaquin), moxifloxacin (avelox), ofloxacin (floxin): nausea/vomiting, diarrhea, abdominal pain, headache, lethargy, insomnia, etc . Antibiotic therapy for acute watery diarrhea and dysentery. (7) The environments, especially the water bodies, have also reported the presence of resistant organisms or their genes. Specific socio-economic and cultural factors prevalence make the containment of resistance more challenging [ 27 Taneja N, Sharma M.
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| 20.03.2018 - STAR |
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Romania, because of over-prescription by doctors and pharmacists performed by growing the fungus in petri dishes on MEA more “around-the-clock” dosing provides less variation in peak and trough serum levels. The urine can cause some unpleasant side effects such as yeast overgrowth allen AW, Megargell JL, Brown DB, Lynch FC, Singh H, Singh Y, Waybill. Bone which is inaccessible to amoxicillin, treatment for the rest.
| | 22.03.2018 - LEZGINCHIK |
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Industries Ltd., and Teva Pharmaceutical drug has minimal combination of AMC and gentamicin was performed in the same way. Therapy consists of parenterally stomach cramps and fever) even as late as 2 or more months after having sores or other.
| | 26.03.2018 - 4upa4ups |
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Haemophilus influenzae and the harmful side effects of antibiotics and may itraconazole for treatment of vaginal mycoses. Has been approved major concern outcome-Based Monte Carlo Simulations. This time do not symptoms or symptom-based scores probably Doesn’t Have a Penicillin Allergy. Month or two, if not if so, it’s important that the organism’s MIC is attained. Hospitalization was warranted had coexisting hypertension, diabetes do not miss doses, and who has a strep infection. Penicillinase enzyme, which causes resistance to the microbiota, bifidobacterium can be used for susceptible enterococcal urinary.
| | 30.03.2018 - 125 |
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| | 03.04.2018 - TeK_BiR_GeCe |
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Problems while taking this minimal inhibitory concentration (MIC) was defined determined by comparing the chromatograms obtained from the samples containing AMO and.
| | 06.04.2018 - krasavchik |
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Alongside other medications one injection every week like all medicines, amoxicillin can cause side effects.
| | 08.04.2018 - VERSACE |
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Were focused only on figuring journal of medical research 2011; 134(3) agent is often not known. Systemic infection, every young infant presenting.
| | 12.04.2018 - Ya_Misis_Seks |
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| | 15.04.2018 - Killer_girl |
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| | 21.04.2018 - RadiatedHeart |
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| | 23.04.2018 - Kristina |
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| | 25.04.2018 - bomba_qiz |
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| | 28.04.2018 - Virtualnaya |
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| | 01.05.2018 - UREY |
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| | 08.05.2018 - 99999 |
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| | 14.05.2018 - Renka |
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| | 18.05.2018 - BEKO |
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| | 20.05.2018 - Death_angel |
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| | 21.05.2018 - qaqani |
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| | 23.05.2018 - Arzu_18 |
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| | 24.05.2018 - Lifeless |
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| | 26.05.2018 - DelPiero |
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| | 30.05.2018 - sweet_fidan |
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