Order amoxil

Transmural necrosis of the small bowel occurs with this infection and surgery may be indicated. Penicillin G is the drug of choice and alternative antibiotics includeВ metronidazole,В clindamycin, orВ chloramphenicol.

Actinomycosis can manifest as a disease of the oral-cervicofacial area, thoracic area, or as abdominal disease.В Actinomyces В species are causative organisms, particularly Actinomyces israelii .

It is important to treat this infection with high doses for a prolonged period of time due to decreased antimicrobial penetration into scarred areas.

Penicillin G intravenously at doses of 18-24 mu daily for 2-6 weeks is the treatment of choice for most actinomycosis infections, followed up with oral penicillin VK or amoxicillin for 6-12 months.В In vitro В susceptibility ofВ Actinomyces В to oxacillin and dicloxacillin is poor; therefore these drugs should be avoided (134).

Penicillins are important agents in the therapeutic armamentarium of antimicrobial agents, being efficacious with relatively limited toxicity profiles.

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