Amoxicillin 125mg 5ml for babies

In the range 250 to 3000 mg the bioavailability is linear in proportion to dose (measured as C max and AUC).

The absorption is not influenced by simultaneous food intake.

Haemodialysis can be used for elimination of amoxicillin. About

18%

Following intravenous administration, amoxicillin has been found in gall bladder, abdominal tissue, skin, fat, muscle tissues, synovial and peritoneal fluids, bile and pus. Amoxicillin does not adequately distribute into the cerebrospinal fluid. From animal studies there is no evidence for significant tissue retention of drug-derived material. Amoxicillin, like most penicillins, can be detected in breast milk (see section 4.6). Amoxicillin has been shown to cross the placental barrier (see section 4.6).

Amoxicillin is partly excreted in the urine as the inactive penicilloic acid in quantities equivalent to up to 10 to 25% of the initial dose.

The major route of elimination for amoxicillin is via the kidney. Amoxicillin has a mean elimination half-life of approximately one hour and a mean total clearance of approximately 25 l/hour in healthy subjects.

Approximately 60 to 70% of the amoxicillin is excreted unchanged in urine during the first 6 hours after administration of a single 250 mg or 500 mg dose of amoxicillin. Various studies have found the urinary excretion to be 50-85% for amoxicillin over a 24 hour period. Concomitant use of probenecid delays amoxicillin excretion (see section 4.5).

The elimination half-life of amoxicillin is similar for children aged around 3 months to 2 years and older children and adults.

For very young children (including preterm newborns) in the first week of life the interval of administration should not exceed twice daily administration due to immaturity of the renal pathway of elimination.

Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

Following oral administration of amoxicillin/ to healthy males and female subjects, gender has no significant impact on the pharmacokinetics of amoxicillin.

The total serum clearance of amoxicillin decreases proportionately with decreasing renal function (see sections 4.2 and 4.4).

Hepatically impaired patients should be dosed with caution and hepatic function monitored at regular intervals.

Non-clinical data reveal no special hazard for humans based on studies of safety pharmacology, repeated dose toxicity, genotoxicity and toxicity to reproduction and development. Carcinogenicity studies have not been conducted with amoxicillin. This leaflet is for parents and carers about how to use this medicine in children. Our information sometimes differs from that provided by the

manufacturers

Keep it somewhere safe so that you

can

It is important that your child takes this medicine in the way that your doctor has told you to so that it kills the harmful bacteria and gets rid of their infection.

Capsules: 250 mg and 500 mg Liquid medicine (suspension): 125 mg or 250 mg in 5 mL and 125mg in 1.25ml: these may contain a small amount of sugar. This should be first thing in the morning, early afternoon and at bedtime. Ideally, these times should be at least 4 hours apart.

Your doctor will work out the amount of amoxicillin (the dose) that is right for your child. It is

important

Capsules should be swallowed whole with a glass of water, milk or squash (but not juice).

Measure out the right amount using an oral syringe or a medicine spoon.

Do not use a kitchen teaspoon as it will not give the right amount.

You can also dilute the right amount of medicine (measured with a medicine spoon) in a small amount of water or milk.

Your child should start to get better after taking the medicine for 2 days. It is important that they take the whole course of the medicine that has been prescribed. If your child is sick less than 30 minutes after having a dose of amoxicillin, give them the same dose again. If your child is sick more than 30 minutes after having a dose of amoxicillin, you do not need to give them another dose.

If your child is sick again, seek advice from your family doctor, pharmacist, hospital doctor or nurse.

If you remember up to 1 hour after you should have given a dose, give the missed dose. If you remember after this time, do not give the missed dose.

You are unlikely to cause harm if you give an extra dose of amoxicillin by mistake.

If you think you may have given your child too much amoxicillin, contact your doctor or local NHS services (details at end of leaflet).

Have the medicine container or packet with you if you telephone for advice. We use medicines to make our children better, but sometimes they have other effects that we don’t want (side-effects). Side-effects are rare with amoxicillin and do not usually last for long. They will get better after a day or two as your child’s body gets used to the medicine, and should go away when the treatment course is finished. If your child is short of breath or is wheezing, or their face, lips or tongue start to swell, or they develop a rash, they may be allergic to amoxicillin. Take your child to hospital or phone for an ambulance straight away.

If your child develops a lumpy red rash, tell your doctor, as your child may have glandular fever or another viral infection.

Your child may have diarrhoea, stomach pains, feel sick or be sick (vomit) when they first start to take amoxicillin. Encourage them to drink water to replace any fluid they have lost.

Contact your doctor or local NHS services (

details

Do not give your child any medicine to stop the diarrhoea, unless your doctor has told you to. You may see white patches inside your child’s mouth and throat, and girls may get itching or soreness around the vagina. This is caused by a fungal infection called thrush. If you think your child may have thrush, contact your doctor or pharmacist for advice. There may, sometimes, be other side-effects that are not listed above.

If you notice anything unusual and are concerned, contact your doctor. You can report any suspected side-effects to a UK safety scheme at www.mhra.gov.uk/ yellowcard. It is important that your child completes the course of

antibiotic

the

for

that

Many common illnesses, such as sore throats, colds, coughs and flu, are caused by viruses.

Your doctor will not prescribe antibiotics for these illnesses. Try to give the antibiotic at about the

same

Give old/unused antibiotics to your pharmacist to dispose of. Only give the antibiotic to the child it was prescribed for.

Never give it to anyone else, even if their condition appears to be the same, as it could do harm.

If you think someone else may have taken the medicine by accident, contact your doctor for advice.

Can other medicines be given at the same time as amoxicillin? You can give your child medicines that contain paracetamol or ibuprofen, unless your doctor has told you not to.

Check with your doctor or pharmacist before giving any other medicines to your child. Is there anything else I need to know about amoxicillin? Amoxicillin is a type of antibiotic called penicillin.

Your child should not have amoxicillin if they are allergic to any penicillin antibiotic.

If your child has ever had an allergic reaction or other reaction to any medicine, tell your doctor before giving amoxicillin.

Keep this medicine in a cupboard, away from heat, direct sunlight and excess moisture (do not

keep

Augmentin and amoxicillin are two types of antibiotics.

Antibiotics help treat bacterial infections that may be too strong for the body’s immune system to clear. Amoxicillin is a very common type of antibiotic, and Augmentin contains amoxicillin and clavulanate or clavulanic acid, which may make it more effective against some types of infection. In this article, learn about the difference between the two antibiotics and the potential side effects of each. Share on Pinterest Doctors commonly prescribe Augmentin or amoxicillin for bacterial infections. Augmentin and amoxicillin are both in the penicillin drug class, which is a group of common antibiotics. Augmentin contains amoxicillin, as the primary ingredient, and it also contains clavulanate. Clavulanate can help treat infections caused by antibiotic-resistant bacteria.

The

It is important to note

that

Taking antibiotics unnecessarily may make them less effective over time and lead to antibiotic resistance. Doctors

use

It is a conventional drug that doctors prescribe to treat bacterial infections in children and adults. Children may be more likely to receive prescriptions for amoxicillin, as it is effective against several childhood infections, and it tends not to cause many troubling side effects.

Amoxicillin combats a wide range of bacteria, including gram-positive and gram-negative strains. Doctors may recommend amoxicillin for infections such as: ear infections strep throat respiratory infections, including pneumonia and bronchitis tonsillitis urinary tract infections (UTIs) Helicobacter pylori infections skin infections sexually transmitted infections, such as gonorrhea or chlamydia.

It is a mixture of amoxicillin and clavulanate or clavulanic acid. It stops the enzymes that infectious bacteria produce to make themselves more resistant to antibiotics. Because it contains clavulanate, Augmentin can treat some strains of bacteria that may be resistant to traditional antibiotics.

As a result, the drug may be more effective for a wider range of bacteria.

Doctors may prescribe Augmentin to treat the same infections as amoxicillin. They may also prescribe it to treat infections that could be more drug-resistant, including: sinus infections stubborn or chronic ear infections laryngitis pharyngitis severe skin infections, such as abscesses or erysipelas bacterial infections related to chronic obstructive pulmonary disease. Doctors may also prescribe Augmentin for people who have recurring infections, such as UTIs or strep throat. Amoxicillin and Augmentin share some side effects, while others are specific to Augmentin.

As both drugs contain amoxicillin, they have some common side effects, such as: heartburn abdominal pain nausea vomiting diarrhea that lasts longer than 1 day easy bruising bloody diarrhea rashes.

Augmentin and amoxicillin may also alter the healthy growth of bacteria in the intestines.

This may lead to a temporary imbalance in the intestinal flora. People who frequently use antibiotics may have a higher risk of these issues, because their gut bacteria may have less time to recover. According to the authors of a 2015 review, consuming probiotic foods after a round of

antibiotics

These are fungal infections that need antifungal treatment. In very rare cases, some people may also experience seizures or low blood or platelet levels after taking these

antibiotics

It is also

possible

Anyone experiencing these symptoms should seek emergency medical care. Augmentin may cause additional side effects, including: bloating gas a headache. Also, Augmentin may lead to an overgrowth of bacteria called Clostridium difficile . This can cause severe diarrhea that requires treatment to prevent complications. It is essential to report any severe side effect to a doctor. The United States Food and Drug Administration note that, while Augmentin has a low risk of toxicity, people who take it for a longer period should be under close supervision, as there may be a chance of damage to the kidney or liver. Oral semisynthetic aminopenicillin similar to ampicillin; not stable to beta-lactamases of either gram-positive or gram-negative bacteria; more stable to gastric acid than penicillin; more bioavailable than oral ampicillin; commonly used to treat otitis media, bronchitis, sinusitis; also used in combination regimens for H.

Amoxicillin/Amoxicillin Trihydrate/Amoxil

Oral

The American Heart Association (AHA) recommends amoxicillin extended-release as an alternative to penicillin V for rheumatic fever prophylaxis.

1 g PO once daily or 500 mg PO twice daily for 10 days.

The American Heart Association (AHA) recommends extended-release amoxicillin as an alternative to penicillin V for rheumatic fever prophylaxis.

25 mg/kg/dose (Max: 500 mg/dose) PO twice daily for 10 days is recommended by the Infectious Diseases Society of America (IDSA).

Alternatively, 50 mg/kg/dose PO once daily (Max: 1 g/dose) for 10 days is recommended by The American Heart Association (AHA) as an alternative to penicillin V.